Video below shows the largest SpikeFun simulation yet - with 16.7 million neurons and 2.1 billion synapses. This is, to my best knowledge, the largest spiking neural network simulation achieved on a home PC. Here are few fact about the simulation in the video below:
~16.7 million neurons with ~2.1 billion synapses
25 types of cortical, thalamic and brainstem (pontine tegmentum) neurons with multiple compartments
Tsodyks-Markram synapse model, including depressing and facilitating synapses (short-term plasticity) and differential axonal signalling
AMPA, NMDA, GABAa and GABAb synaptic receptors
Long-term plasticity modeled using Spike-timing dependent plasticity (STDP)
Local circuit connectivity based on cat primary visual cortex (V1) cell statistics
Long-range connectivity following data collected using Diffusion Spectrum Imaging (DSI)
Axonal bifurcations with multi-site targets for pyramidal neurons, variable axonal delays (myelinated/non-myelinated)